Guiterrez C.: eosinophilic oesophagitis (EOE)
Today in the ESPGHAN podcast series we hear from Dr Carolina Gutiérrez Junquera of the Universidad Autónoma de Madrid on eosinophilic oesophagitis (EOE). Dr Gutiérrez Junquera passed in her training through the Complutense University of Madrid and its affiliated hospitals. After a fellowship in the San Francisco bay area, she went home to Spain to develop her interest in various aspects of EOE. She has become prominent as an organiser and evaluator of multi-institutional studies of this disorder. At present she is investigating proton-pump inhibitor (PPI) use in EOE, with focus on several questions: What is the rôle of PPIs in treatment of children with EOE ? What factors, pharmacogenetic and clinical, may predict PPI response in children with EOE ? What do literature reviews and accumulated experience to date suggest be researched in EOE ? Finally, what are the most important changes in the updated ESPGHAN guidelines on diagnosis and management of EOE ? Today’s discussion tries to touch on these various elements – although not necessarily in that order.
Literature :
Gutiérrez-Junquera C et al. Proton pump inhibitor therapy in pediatric eosinophilic esophagitis: Predictive factors and long-term step-down efficacy. J Pediatr Gastroenterol Nutr 2023 Feb 1; 76(2):191-198. doi: 10.1097/MPG.0000000000003660. Epub 2022 Nov 23. PMID: 36416845.
Franciosi JP et al. Medical treatment of eosinophilic esophagitis. Cochrane Database Syst Rev 2023 Jul 20; 7(7):CD004065. doi: 10.1002/14651858.CD004065.pub4. PMID: 37470293. PMCID: PMC10358040.
Papadopoulou A et al. Joint ESPGHAN / NASPGHAN guidelines on childhood eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis. J Pediatr Gastroenterol Nutr 2024 Jan 78(1):122-152. doi: 10.1097/MPG.0000000000003877. Epub 2023 Jul 4. PMID: 38291684.
Dr. Guiterrez favourite song: Hoy puede ser un gran día - Joan Manuel Serrat https://open.spotify.com/track/5YxgSArh0FDP0CEDuZcYnC?si=d70a2941550b48c9
ESPGHAN favourite Songs can be found on Spotify https://open.spotify.com/playlist/0YIHKjxITLEm9XNyHyypTo